Which term describes the sequence of developmental features typically associated with Pierre Robin?

The term that describes the sequence of developmental features associated with Pierre Robin is mandibular hypoplasia sequence. Pierre Robin sequence is characterized primarily by a smaller-than-normal mandible (mandibular hypoplasia), which leads to a series of secondary issues, including cleft palate and glossoptosis (the posterior displacement of the tongue). This sequence is important in understanding the developmental biology behind the series of abnormalities that occur due to the initial defect in jaw development.

The features of this sequence arise because the underdeveloped mandible restricts proper development of the surrounding structures during embryonic growth. This results in complications with airway obstruction and feeding, making early intervention critical in affected individuals.

In contrast to the mandibular hypoplasia sequence, the other sequences mentioned do not relate to Pierre Robin. For instance, the clubfoot sequence typically refers to a different spectrum of limb anomalies, while umbilical hernia sequence and C deficiency sequence are limited to other developmental syndromes that do not directly correlate with the features of Pierre Robin. Thus, understanding the specific characteristics of mandibular hypoplasia helps clarify why this term is correctly associated with Pierre Robin sequence.