Which of the following features is NOT commonly associated with Cri-du-chat syndrome?

Get ready for the American Board of Genetic Counseling exam. Prepare with flashcards and multiple choice questions, each question includes hints and explanations. Ace your exam with confidence!

Cri-du-chat syndrome is a genetic disorder caused by a deletion of part of chromosome 5. The features associated with this syndrome typically include distinct physical characteristics and developmental delays.

Hypertelorism, or widely spaced eyes, is often seen in individuals with Cri-du-chat syndrome, making it a common feature associated with the condition. The "cat-like cry," from which the syndrome gets its name, is another hallmark characteristic, as the unusual cry is due to laryngeal anomalies. Microcephaly, or a smaller than average head size, is frequent in affected individuals as well and is directly linked to the developmental issues associated with the syndrome.

On the other hand, supravalvular aortic stenosis, which is a narrowing of the aorta just above the valve, is typically associated with Williams syndrome, not Cri-du-chat syndrome. Williams syndrome is characterized by a distinct set of cardiovascular issues as well as other cognitive and physical traits that are not features of Cri-du-chat. Therefore, recognizing that supravalvular aortic stenosis is not a common feature of Cri-du-chat syndrome helps to clarify the unique profile of symptoms associated with this genetic disorder.

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