Which is a common hereditary syndrome associated with paragangliomas?

Hereditary Paraganglioma-Pheochromocytoma Syndrome is recognized as a common hereditary condition associated with paragangliomas. These tumors arise from paraganglia, which are neuroendocrine tissues. This syndrome is characterized by the development of paragangliomas and pheochromocytomas, which are tumors of the adrenal glands that can produce catecholamines, leading to various symptoms such as hypertension and palpitations.

The syndrome is primarily linked to mutations in several specific genes, including SDHB, SDHC, and SDHD, which are involved in the succinate dehydrogenase complex. This multifactorial genetic basis contributes to a hereditary predisposition to these types of tumors, making it the most relevant choice regarding paragangliomas.

In contrast, the other options, while associated with various genetic disorders, do not typically present with paragangliomas. Familial Adenomatous Polyposis (FAP) is primarily associated with colorectal cancer and does not involve paragangliomas. Multiple Endocrine Neoplasia type 2A (MEN2A) is characterized by medullary thyroid carcinoma and other endocrine tumors, but it is not primarily known for paragangliomas. Xeroderma