Which inheritance pattern is primarily seen in Coffin-Lowry Syndrome?

Coffin-Lowry Syndrome is primarily associated with an X-linked inheritance pattern, which is indicated by the correct answer. This means that the gene responsible for the condition is located on the X chromosome. Males, who have only one X chromosome, are more severely affected by this syndrome, as they will express the condition if they inherit the mutated gene. Females, having two X chromosomes, may be carriers and show milder symptoms due to the potential presence of a normal allele on their second X chromosome.

Understanding the specific inheritance pattern of Coffin-Lowry Syndrome helps in genetic counseling, as it informs families about the risks of passing the condition to offspring. In particular, it is important to know that the affected fathers will pass the condition to all of their daughters, who will then become carriers, while their sons will not be affected. This knowledge allows for better family planning and risk assessment for future generations.