Which deletion syndrome is associated with micrognathia and pits or tags?

Wolf-Hirschhorn syndrome is characterized by features that include micrognathia (a condition in which the lower jaw is smaller than normal) and the presence of ear pits or tags. This deletion syndrome results from a deletion on the short arm of chromosome 4, specifically at 4p16.3, and leads to a variety of physical abnormalities and cognitive impairments.

Individuals with Wolf-Hirschhorn syndrome typically exhibit distinct facial features, including a prominent forehead, a broad nasal bridge, and downturned corners of the mouth, alongside the distinctive micrognathia and ear anomalies. The combination of these traits is significant in diagnosing the condition, allowing genetic counselors and healthcare professionals to identify the syndrome based on its characteristic phenotype.

In contrast, the other deletion syndromes listed may present with various clinical features but do not commonly include both micrognathia and pits or tags as defining characteristics. Thus, Wolf-Hirschhorn syndrome stands out as the correct answer in this context.