What anomalies are typically associated with the Potter sequence?

The Potter sequence, also known as Potter's syndrome, results from a severe reduction in amniotic fluid (oligohydramnios), which can lead to a characteristic set of anomalies caused by the compression of the developing fetus. The most common underlying cause of oligohydramnios, leading to the Potter sequence, is renal anomalies, particularly conditions such as renal agenesis or severe dysplasia that impede kidney function and urine production, which contributes to the production of amniotic fluid.

One of the hallmark features of the Potter sequence is the development of hypoplastic lungs. The lungs are dependent on amniotic fluid during fetal development for proper growth and expansion. When there is insufficient amniotic fluid due to renal anomalies, the lungs do not develop adequately, leading to respiratory distress or underdeveloped pulmonary structures at birth.

In contrast, other options presented may include conditions that can occur in various syndromes or developmental issues but do not directly align with the classical features associated with the Potter sequence. Oligohydramnios can indeed lead to various anomalies, but the specific combination of renal anomalies and hypoplastic lungs distinctly marks the clinical profile of the Potter sequence.